1970 - 1973

Study of Pharmaceutical Sciences at the Johann-Wolfgang von Goethe Universität Frankfurt/Main


October 1973 -
September 1987

Scientific asssistent at the Department of Clinical Physiology, Heinrich-Heine-Universität Düsseldorf


July 1977

PhD at the Dept. of Clin. Physiology (Heinrich-Heine-Universität Düsseldorf, Prof. Dr. R. Kaufmann). Thesis: Investigations on the Ca-antagonistic mode of action and the structure-activity relationships of verapamil


December 1982

Habilitation, conferred by the Medical Faculty of the Heinrich-Heine-Universität Düsseldorf.Title of monograph: Ca-antagonists of the aliphatic amine type and structurally related heart-active drugs - Investigations on pharmacological and physico-chemical properties


since 1984

Contributing Editor of "Drugs of Today" and "Drugs of the Future"


January 1989 -
October 1990

Guest scientist at the Deartment for Pharmacochemistry, Vrije Universiteit, Amsterdam, NL(Prof. Dr. Henk Timmerman)


since November 1990

Professorship for Molecular Drug Research at the Heinrich-Heine-Universität Düsseldorf


since 1993

Editor of the book series Methods and Principles in Medicinal Chemistry, WILEY-VCH, Weinheim; together with Hugo Kubinyi and Henk Timmerman (since 2001 Gerd Folkers)


since 2001

Regional Editor of Mini-Reviews in Medicinal Chemistry


since 2005

Editorial Board Member of Medicinal Chemistry and Current Computer-aided Drug Design


October -
November 2011

Visiting Professor at the School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Switzerland